A New Strategy for Discontinuation of Dual Antiplatelet Therapy
نویسندگان
چکیده
منابع مشابه
A New Strategy for Discontinuation of Dual Antiplatelet Therapy
Methods We randomly assigned 2,117 patients with coronary artery stenosis into 2 groups according to DAPT duration and stent type: 3-month DAPT following Endeavor zotarolimus-eluting stent (E-ZES) implantation (E-ZES 3-month DAPT, n 1,059) versus 12-month DAPT following the other DES implantation (standard therapy, n 1,058). We hypothesized that the E-ZES 3-month DAPT would be noninferior to th...
متن کاملA new strategy for discontinuation of dual antiplatelet therapy: the RESET Trial (REal Safety and Efficacy of 3-month dual antiplatelet Therapy following Endeavor zotarolimus-eluting stent implantation).
OBJECTIVES The goal of this study was to evaluate shorter duration (3 months) dual antiplatelet therapy (DAPT) after drug-eluting stent (DES) implantation. BACKGROUND There have been few published reports of prospective randomized clinical studies comparing the safety and efficacy of shorter duration DAPT after DES implantation. METHODS We randomly assigned 2,117 patients with coronary arte...
متن کاملSimultaneous Thrombosis of Two Drug-Eluting Stents After Discontinuation of Dual Antiplatelet Therapy for a Day
Stent thrombosis is rare but can lead to potential severe consequence. The incidence is relative higher in drug-eluting sent than bare-metal stent implantation. Dual antiplatelet therapy is the major treatment to avoid early and late stent thrombosis. Simultaneous two stents thrombosis is rare. Although mechanical or/and procedure factors may predispose to stent thrombosis occurred, simultaneou...
متن کاملPredictors of early discontinuation of dual-antiplatelet therapy: room for improvement.
Drug-eluting stents (DES) have revolutionized the approach to percutaneous coronary interventions and have substantially reduced restenosis compared with bare metal stents.1,2 Despite their advantages, DES are not without disadvantages. In particular, patients who receive DES remain at risk of a 1% to 2% incidence of stent thrombosis, which is often fatal.3,4 Dual-antiplatelet therapy (DAT) in ...
متن کاملPrevention of Premature Discontinuation of Dual Antiplatelet Therapy in Patients With Coronary Artery Stents
Dual antiplatelet therapy with aspirin and a thienopyridine has been shown to reduce cardiac events after coronary stenting. However, many patients and healthcare providers prematurely discontinue dual antiplatelet therapy, which greatly increases the risk of stent thrombosis, myocardial infarction, and death. This advisory stresses the importance of 12 months of dual antiplatelet therapy after...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2012
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2012.06.043